Women Who Often Miscarriage Are at Higher Risk of Heart Disease

Women Who Often Miscarriage Are at Higher Risk of Heart Disease

Women who have miscarriages and don't have children are at a higher risk of heart disease compared to women who have only one or two children, according to a new study.The research findings were published in the Journal of Women's Health as quoted from www.medindia.net. The study also found that women who had five or more children were at an increased risk of cardiovascular disease in the future.During pregnancy, a mother's body changes, such as weight gain and accumulation of abdominal fat, higher cholesterol levels, increased insulin resistance, and changes in heart structure.Although most of the changes that occur during pregnancy are temporary, these changes are known as risk factors for cardiovascular disease in the general population.



Previous research has tried to assess the relationship between pregnancy and childbirth on the one hand and cardiovascular disease on the other. However, due to limitations in this study - including not taking into account breastfeeding history and grouping with women who had never been pregnant with those who had been pregnant but who had miscarriages - the results were inconclusive and sometimes contradictory.In the new study, a team of researchers in the US and the UK analyzed data from more than 8,500 white women and African-American women, aged 45-64 years, in the United States (US).These include data on health services for cardiovascular disease for thirty years (1987-2016), and self-reported data on the number of pregnancies and births, and breastfeeding practices.

Greater Risk

In the study population, 138 women reported having had a miscarriage and had no children born alive. As many as 3,108 women have one or two children born alive, 3,126 have 3-4 children alive, and 1,694 have five or more children born alive.The researchers found that women who had a miscarriage and did not have children born alive were at a 64% greater risk of developing coronary heart disease, and a 46% greater risk of heart failure compared to women with one or two children.
Women with five or more births have a 38% higher risk of having a serious heart attack, regardless of how long they breastfeed.The research team called bahwan that there might be several possible reasons for the relationship between cardiovascular risk and multiple births.


Repeated pregnancy can produce long-term changes in the body including weight gain, especially around the waist, and increased cholesterol levels in the blood. Also, the number of children includes other factors, including raising children, age at menopause and health conditions.Therefore, the researchers said it was unclear whether the increased risk of heart failure, coronary heart disease, and heart attacks reflected the direct impact of repeated pregnancies, or stress associated with raising many children, or both.

Causes of Major Death

Increased risk of coronary heart disease and heart failure was found in women with previous pregnancies, but no children were born, perhaps reflecting an increased risk previously identified after a history of miscarriage.Several mechanisms have been proposed to underlie the relationship between miscarriage and coronary heart disease, including immune disorders, chronic diseases and endothelium dysfunction (cells that line the inside of blood vessels).

"Conditions like heart disease and stroke are the main causes of death in women in developed countries, and it's important for us to understand why this happens," said Dr. Clare Oliver-Williams, a young researcher at Homerton College who works in the Department of Public Health and Primary Care at Cambridge University.

"Our research shows that there is a relationship between the risk of cardiovascular disease, also miscarriage and having multiple births."

"This study is not designed to emphasize and worry women, especially those who have miscarriages. Instead, we want to empower women with knowledge that will help them to reduce their risk."

"Most women know at the age of 40 how many children and miscarriages they experience, which have had heart attacks and strokes many years before. This provides an opportunity to make lifestyle changes, such as exercise and diet that can help reduce the risk of cardiovascular disease . "